Name | Lactobionic acid |
Synonyms | LACTOBIONIC ACID Lactobionic acid LACTOBIONIC ACID FREE ACID 4-[β-D-Galactosido]-D-gluconic acid 4-O-β-D-Galactopyranosyl-D-gluconic acid 4-O-beta-D-galactopyranosyl-D-gluconic acid 4-O-BETA-D-GALACTOPYRANOSYL-D-GLUCONIC ACID D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl- Lactobionic Acid (mixture of Acid form and Lactone form) |
CAS | 96-82-2 |
EINECS | 202-538-3 |
InChI | InChI=1/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1 |
Molecular Formula | C12H22O12 |
Molar Mass | 358.3 |
Density | 1.4662 (rough estimate) |
Melting Point | 113-118°C(lit.) |
Boling Point | 410.75°C (rough estimate) |
Specific Rotation(α) | 22.8 º (c=10, H2O) |
Flash Point | 319.1°C |
Water Solubility | 10 g/100 mL |
Solubility | Solubility in water: 10G/90 ML water, slightly soluble in glacial acetic acid, slightly soluble in methanol and ethanol, almost insoluble in ether. |
Vapor Presure | 7.15E-35mmHg at 25°C |
Appearance | White crystal |
Color | White to Off-white |
Merck | 5342 |
BRN | 95054 |
pKa | 3.28±0.35(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 26 ° (C=8.8, H2O) |
MDL | MFCD00078147 |
Use | An inhibitor of matrix metalloproteinases |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 1 |
HS Code | 29400000 |
third-generation fruit acids | lactobionic acid is a third-generation fruit acid, which is less irritating than the first generation, and better than the second generation of acid on the cleaning of the pores. Composed of a molecule of galactose and a molecule of gluconic acid, is a polyhydroxy biological acid. The structure of lactobionic acid has eight groups of hydroxyl water groups, which can capture a large number of water molecules. Both similar to the effect of acid (exfoliation, blackhead acne, prevention and mitigation of closed mouth, shrink pores, acne, etc.), and antioxidant, anti-aging, whitening and other effects. |
efficacy and action | lactobionic acid (BionicAcid) was developed by the U. S. EugeneJ.Van Scott and Chinese-American director Yu Ruijin (Dr.RueyJ.Yu) research and development of the third generation of fruit acid, not only adhering to the unique effect of fruit acid, but also mild nature, with excellent moisturizing, antioxidant and skin repair effect, not only suitable for sensitive skin, it is also an indispensable tool for global dermatologists in adjuvant therapy and home maintenance. when lactobionic acid acts on the epidermis, it reduces the cohesive force between keratinocytes, accelerates the exfoliation of aged keratinocytes, enhances the metabolic rate of epithelial cells, and promotes skin renewal, it also makes the epithelial cells more orderly, and the stratum corneum becomes smooth and fine. At the same time, lactobionic acid can also make the keratinizing embolism around the pores easy to fall off, and smooth the hair follicle tube, effectively prevent pore obstruction. As for the effect of lactobionic acid on the dermis, it can stimulate the proliferation and rearrangement of hyaluronic acid, mucopolysaccharide, collagen and elastic fibers, so that the water content of the skin increases, and the skin becomes firm and elastic, fine lines and wrinkles also decrease. The main function of lactobionic acid on the skin is the role of anti-wrinkle. |
biological activity | Lactobionic acid is an α-Oxo acid with antioxidant activity, it is used in the development of skin cosmeceuticals. |
Use | pharmaceutical intermediates |